Episentum presents at K4DD meeting, Berlin, October 16-18 2017

Episentum will present a poster at the K4DD meeting “Binding kinetics: Time is of the essence” in Berlin, October 16-18 2017. K4DD is an Innovative Medicines Initiative (IMI) program on Kinetics in Drug Discovery. The title of our poster is “Kinetic Analysis of Small-Molecule Binding with Label-Enhanced SPR”.

Looking forward to getting and update on binding kinetics, and to presenting the potential of LE-SPR in this area. For any information on LE-SPR prior to the meeting, or to book a one-to-one meeting, please contact us at info@episentum.com.

 

Presentation at Drug Discovery 2017 Meeting, Liverpool, UK, October 3-4 2017

Episentum will give an oral presentation and exhibit a poster at the Drug Discovery 2017 Meeting, Liverpool, UK, 3-4 October 2017. The title of both contributions is “Label-Enhanced SPR for Improved Surface Plasmon Resonance Analysis of Small Molecules and Biomolecules”.

Looking forward to meeting you in Liverpool! For any information on LE-SPR prior to the meeting, or to book a one-to-one meeting, please contact us at info@episentum.com.

 

New product launch: LE-SPR Validation Kit

We are now offering a Label-Enhanced SPR Validation Kit B9003 to be used as a learning tool or test tool for Biacore™ users that want to get a first acquaintance to the LE-SPR technology. The Validation Kit can also be used to test a SPR instrument, or as a positive control sample during regular LE-SPR analysis. More information on the Validation Kit is found in our recently published Episentum Technical Note 012.

To get a free copy of our Technical Note 012 or for any other enquiries, please contact us at sales@episentum.com.

 

Episentum presents at the NovAlix conference Biophysics in Drug Discovery, Strasbourg, France, 6-9 June 2017

Episentum will present a poster on Label-Enhanced SPR at the NovAlix conference Biophysics in Drug Discovery, Strasbourg, France, 6-9 June 2017. We will display the enhanced sensitivity in small molecule analysis, as well as the enhanced specificity and the dual-colour capabilities in protein analysis.

We’re looking forward to meeting with lots of SPR scientists and other biophysicists, including old and new customers. For any information on LE-SPR prior to the meeting, or to book a one-to-one meeting, please contact us at info@episentum.com.

 

New LE-SPR publication

Label-Enhanced SPR (LE-SPR) can be used to clearly confirm binding site specificity. Brandon Garcia and Brian Geisbrecht at Kansas State University and their co-workers have used LE-SPR in a very elegant manner to study small-molecule inhibitors of the complement system using a standard Biacore™ T200 instrument. Taking advantage of the greatly simplified interpretation of LE-SPR data, binding site specificity was unambiguously confirmed in a way that would have been hard to achieve with conventional SPR.

The full study is recently published in The Journal of Immunology.

For more information about the LE-SPR technology, please contact us directly at info@episentum.com.

 

Episentum presents at the Advances in Drug Discovery meeting, Cambridge, UK, 6-7 March 2017

Episentum will present a poster at the Advances in Drug Discovery meeting, Cambridge, UK, 6-7 March 2017. The poster will demonstrate how Label-Enhanced SPR can improve the surface plasmon resonance analysis of small molecules as well as larger biomolecules.

We’re looking forward to meeting with lots of SPR users, including old and new customers. For any information on LE-SPR prior to the meeting, or to book a one-to-one meeting, please contact us at info@episentum.com.

 

End-of-year offer: Free Label-Enhanced SPR software

To celebrate the approaching Holiday Season, we’re offering free licenses to our Label-Enhanced SPR software. We want to help more scientists get started with LE-SPR, and we also want to reward our existing customers. So here’s the offer:

  • Buy 1 mg of any Episentec™ dye reagent – get a free 3-month full version license to our EpiGrammer™ software.
  • Buy 2 mg of any Episentec™ dye reagents – get a free 6-month full version license to our EpiGrammer™ software.
  • And, as always, we include generous technical support on the implementation of Label-Enhanced SPR to all our customers.

For any enquiries, please contact us at sales@episentum.com.

 

Simple solvent correction in SPR

We have published a new Application Note 025 on the simple and efficient correction of solvent effects in SPR. Label-Enhanced SPR is immune to bulk refractive index variations, so even very large variations in sample solvent composition can be tolerated.

This is especially beneficial when analysing small molecules or fragments in solutions with varying DMSO content. However, the same technique can be used to treat bulk disturbances in general, e.g., the occurrence of varying glycerol concentrations in antibody preparations.

For a copy of the new Application Note 025, or for any other enquiries, please contact us at sales@episentum.com.

 

Episentec evolves into Episentum

Episentec, the company that developed the pioneering Label-Enhanced SPR technology, is now evolving into Episentum. We do this change to highlight the extension of our product range.

Episentum still offers the same high-performance Episentec™ reagents and EpiGrammer™ software for Label-Enhanced SPR, and the same high level of technical support on the implementation of the technology.

We will continue developing and offering products that improve the performance of biosensor instruments, and we’re looking forward to continue serving our customers – old as well as new. For any enquiries, please contact us at sales@episentum.com.

 

New Products: Monoclonal Antibodies

Through our collaboration with Biosensor Applications AB, a leader in the development of mobile equipment for drugs and explosives detection, we are now able to offer highly specific, monoclonal antibodies against drugs of abuse. All antibodies are extensively purified using state-of-the art methodology, carefully quality controlled, and functionally characterized using QCM (quartz crystal microbalance) and SAW (surface acoustic wave) biosensors. Recommended applications are biosensors, optical as well as gravimetric, ELISA, and similar applications requiring high quality, primary antibodies.

Please check out our Monoclonal Antibodies page for more info. For any enquiries and orders regarding antibodies, please contact us at: sales@episentum.com.